The cryopreservatives DMSO and pentastarch are used to:

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The cryopreservation of the product is usually accomplished by the addition of 10% dimethyl sulfoxide (DMSO)and autologous plasma or 5% DMSO with 6% pentastarch and 4% human albumin.DMSO and pentastarch are thought to keep the cells from dehydrating during the freezing process,which would cause them to lyse.The product is then frozen in a controlled-rate freezer,which reduces the temperature of the product by 1° to 3° C a minute,or by so-called dump freezing in a -80° C freezer.After the product is frozen,it is kept in a liquid nitrogen freezer,in the vapor or liquid phase,until the time of transplantation.

The Cryopreservatives DMSO and Pentastarch Are Used To