Neil accidentally ingests a substance that activates the complement cascade in the absence of bound antibodies.This substance would
A) produce a fever.
B) cause extensive cellular damage.
C) increase circulation of lymph.
D) activate blood clotting.
E) prevent inflammation.

Question

Quizplus · Accepted Answer

Activation of the complement cascade in the absence of bound antibodies can cause extensive cellular damage by triggering the formation of membrane attack complexes (MACs) on cell surfaces. This can result in cell lysis, inflammation, and tissue damage. A fever may also occur as a result of the inflammatory response, but it is not a direct effect of complement activation. Activation of the complement cascade does not directly increase circulation of lymph or activate blood clotting, and it is not known to prevent inflammation.

Neil Accidentally Ingests a Substance That Activates the Complement Cascade