An elevated IgM titer typically indicates an active infection while an elevated IgG titer does not distinguish between active and past infections.

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An elevated IgM titer indicates an active infection because IgM antibodies are produced early in an immune response. IgG antibodies, on the other hand, are produced later in the immune response and can persist for long periods of time, even after the infection has been cleared. Therefore, an elevated IgG titer does not distinguish between active and past infections.

An Elevated IgM Titer Typically Indicates an Active Infection While