A patient develops a high fever due to a Gram-negative pathogen.Which of the following is a certain mediator of illness in this case?

Question

Quizplus · Accepted Answer

Gram-negative pathogens contain endotoxins (lipopolysaccharides) in their cellular membrane, which are released upon bacterial death or lysis and can lead to fever, sepsis, and other symptoms of illness. Exotoxins are secreted by the bacteria and can also cause illness, but their presence cannot be assumed in all cases of Gram-negative infection. Therefore, the certain mediator of illness in this case is endotoxin (choice A).

A Patient Develops a High Fever Due to a Gram-Negative