During chronic inflammation when the macrophages are unable to protect the host from tissue damage,the body attempts to wall off and isolate the site by forming a _________.

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During chronic inflammation, when the macrophages are unable to protect the host from tissue damage, the body attempts to wall off and isolate the site by forming a granuloma. A granuloma is a structure that includes a cluster of immune cells, such as macrophages and lymphocytes, along with fibroblasts and collagen. It is a form of chronic inflammation and it represents the body's attempt to contain and isolate foreign substances or persistent infections to prevent their spread. A clot is a mass of coagulated blood that forms inside a blood vessel or in the heart, it does not provide isolation from the inflammatory site. A cyst is a fluid-filled sac that can form in different parts of the body and it also does not provide isolation from the inflammatory site. A vesicle is a small blister-like structure that contains fluid and is not related to chronic inflammation.

During Chronic Inflammation When the Macrophages Are Unable to Protect