Coxiella burnetii reproduces in the ______________ of a eukaryotic host cell.

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Coxiella burnetii is an obligate intracellular bacterium that can survive within phagolysosomes of eukaryotic host cells. It replicates by forming large vacuoles called parasitophorous vacuoles (PV) that avoid fusion with lysosomes and provide a safe environment for the bacteria to replicate. The bacteria can manipulate the host cell's endosomal pathway by inhibiting phagosome-lysosome fusion and modifying the PV membrane to allow for nutrient acquisition and waste disposal. Therefore, Coxiella burnetii reproduces in the phagolysosome of a eukaryotic host cell.

Coxiella Burnetii Reproduces in the ______________ of a Eukaryotic Host