The proteome refers to the collection of open reading frames in a genome.

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The proteome refers to the entire complement of proteins that are expressed by a genome, not just the open reading frames. Open reading frames are simply sequences of nucleotides that are potentially translatable into protein, but not all open reading frames actually translate into functional proteins. The proteome includes all of the proteins that are actually produced by a cell, including those that result from alternative splicing, post-translational modifications, and other processes.

The Proteome Refers to the Collection of Open Reading Frames