Prior to secretion,Gram-negative bacterial proteins are translocated across one membrane while Gram-positive proteins are translocated across two membranes.

Question

Quizplus · Accepted Answer

Gram-negative bacteria have both an inner (cytoplasmic) and an outer membrane, so proteins destined for secretion must be translocated across two membranes. Gram-positive bacteria, on the other hand, have only one membrane (the cytoplasmic membrane) and a thick peptidoglycan layer, so their proteins are translocated across a single membrane.

Prior to Secretion,Gram-Negative Bacterial Proteins Are Translocated Across One Membrane