One way in which small viruses package more information into a very small genome is to use overlapping genes so that the same base sequence is read in more than one reading frame.

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Overlapping genes allow for multiple proteins to be encoded within a small stretch of DNA, increasing the amount of information that can be packed into a small genome. This is achieved by having different reading frames that start at different points within the same stretch of DNA bases. As a result, different proteins can be synthesized depending on which reading frame is used.

One Way in Which Small Viruses Package More Information into a Very