The mechanism of pathogenesis by prions may involve a conformational change in the prion protein (PrP)to an abnormal form.

Question

Quizplus · Accepted Answer

This is true. The abnormal form of the prion protein (PrPSc) is believed to induce a conformational change in normal PrP, leading to the formation of more abnormal PrPSc and ultimately resulting in the accumulation of these misfolded proteins and neurodegeneration.

The Mechanism of Pathogenesis by Prions May Involve a Conformational