Sedimentation coefficients are proportional to the molecular weight of a particle and are not affected by the volume and shape of the particle.

Question

Quizplus · Accepted Answer

Sedimentation coefficients are affected by both molecular weight and the shape and volume of the particle being measured. This is because the frictional coefficient, which is related to the shape and volume of the particle, also affects the sedimentation rate. Therefore, larger or more compact particles will sediment at a faster rate than smaller or more elongated particles with the same molecular weight.

Sedimentation Coefficients Are Proportional to the Molecular Weight of a Particle