What Role Did the Firm N

What role did the firm N.W.Ayer & Son play in the history of U.S.advertising?

A) It was the first printer to use illustrations in its ads.
B) It was the first manufacturer to use national advertising.
C) It was the first ad agency to charge a commission based on the "net cost of space."
D) Its advertising claims were the first of its kind, examined by the Food & Drug Administration.
E) It published the first colonial newspaper with ads.