Which of the Following Is True of the Functions of Pain

Which of the following is true of the functions of pain?

A) Pain is triggered by activation of Pacinian corpuscles.
B) Pain can be triggered by tissue damage within the body.
C) Opiates enhance pain reactivity.
D) Emotional events mostly decrease the aversiveness of pain stimuli.
E) Activation of ACC neurons is involved in the long-term consequences of pain.