Disruption of the hypocretin gene produces symptoms of narcolepsy.

Name: Disruption of the hypocretin gene produces symptoms of narcolepsy.
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Narcolepsy is caused by a deficiency in the neurotransmitter hypocretin, which is produced by neurons in the hypothalamus. Disruption or damage to the hypocretin gene can result in a lack of hypocretin production, leading to narcoleptic symptoms such as excessive daytime sleepiness, sleep attacks, and cataplexy (sudden loss of muscle tone).

Disruption of the Hypocretin Gene Produces Symptoms of Narcolepsy