What Is One Reason Why Tumor Suppressor Genes Make Poor

What is one reason why tumor suppressor genes make poor drugable targets?

A) The tumor suppressor proteins may not even be produced.
B) Tumor suppresor mutations generally result in a greater activity of the protein so that inhibiting the protein is more difficult.
C) It is difficult to distinguish with a drug the normal and mutated forms of the tumor suppressor proteins.
D) It is difficult to get the drugs that can target tumor suppressor proteins into cancer cells.