Gain-of-function mutations might involve which of the following?
A)deletion of a promoter region
B)constitutive activation of an enzyme
C)a synonymous mutation
D)None of the choices is correct.

Question

Quizplus · Accepted Answer

Gain-of-function mutations involve changes in the DNA sequence that lead to an increased activity or new function of a protein. Constitutive activation of an enzyme, as in choice B, is an example of a gain-of-function mutation. Deletion of a promoter region (choice A) could decrease the expression of a gene, while a synonymous mutation (choice C) does not affect the amino acid sequence of a protein and is unlikely to result in a gain of function. Therefore, the correct answer is B.

Gain-Of-Function Mutations Might Involve Which of the Following