Currently the two main vectors for delivery of therapeutic genes for human gene therapy are
A)AAV and retroviruses
B)AAV and Agrobacterium
C)Retroviruses and Agrobacterium
D)AAV, retroviruses and Agrobacterium

Question

Quizplus · Accepted Answer

AAV and retroviruses are currently the most commonly used vectors for human gene therapy. AAV is preferred because it has the ability to target specific cell types and has a low immunogenicity. Retroviruses integrate their genetic material into the host genome, allowing potentially long-lasting gene expression. However, they have the potential for insertional mutagenesis, which can lead to oncogenesis. Agrobacterium is commonly used in plant genetic engineering but is not currently used as a vector for human gene therapy.

Currently the Two Main Vectors for Delivery of Therapeutic Genes