What is the relationship between methylation and genomic imprinting?
A)Differential methylation of alleles in males and females resuilts in only one of the parental alleles being transcriptionally active in the offspring.
B)Methylation of alleles silences the alleles from both parents, no alleles are transcriptionally active.
C)Reversible methylation in the males alleles results in the males alleles only being expressed late in development.
D)Reversible methylation in the females alleles results in the females alleles only being expressed late in development.

Question

Quizplus · Accepted Answer

Methylation plays a crucial role in genomic imprinting. Differential methylation of alleles in males and females results in only one of the parental alleles being transcriptionally active in the offspring. This process is known as genomic imprinting. Methylation marks on the silenced allele prevent its expression in the offspring, leading to monoallelic expression of imprinted genes.

What Is the Relationship Between Methylation and Genomic Imprinting