In the trp operon, attenuation occurs through translation of two Trp codons in the leader sequence.What would happen if these two codons were mutated to stop codons?

Question

Quizplus · Accepted Answer

In the trp operon, the presence of tryptophan allows for the efficient translation of the leader peptide, preventing the formation of a hairpin loop formed by regions 1 and 2 of the leader sequence. This allows for the formation of the antiterminator loop (formed by regions 2 and 3) and transcription of the structural genes. If the Trp codons in the leader sequence were mutated to stop codons, translation of the leader peptide would be interrupted, leading to the formation of a hairpin loop between regions 1 and 2. This would facilitate the binding of region 3 to region 4, resulting in transcription termination and repression of the structural genes. Therefore, C is the correct answer.

In the Trp Operon, Attenuation Occurs Through Translation of Two