How do chromosomal rearrangements generate new gene products?
A)Chromosome sets from different species
B)Translocations may result in the fusion of two different open reading frames.
C)Deletions may remove regulatory regions of genes.
D)Inversions may result in genes moving from a region of euchromatin to a region of heterochromatin.

Question

Quizplus · Accepted Answer

Translocations can result in the fusion of two different open reading frames, leading to the creation of a new gene product that may have a different function or activity. This can occur when two different chromosomes break and their broken ends join together in a new configuration, resulting in the fusion of previously separate genes.

Answer: C
 Deletions can remove regulatory regions of genes, leading to changes in their expression levels or patterns. This can result in the creation of new gene products if the deletion removes specific regulatory elements that normally limit or enhance gene expression.

Answer: D
 Inversions can result in genes moving from a region of euchromatin (open chromatin that is more accessible to transcription factors) to a region of heterochromatin (more tightly packed chromatin that is less accessible to transcription factors). This can impact gene expression and potentially generate new gene products if the inversion causes the gene to be regulated differently or exposes it to new transcriptional machinery.

Answer: A
 Chromosome sets from different species cannot generate new gene products through rearrangements alone, as the rearrangements do not introduce new genetic material. However, hybridization between different species can result in gene transfer and the creation of new gene products through recombination or other mechanisms.

How Do Chromosomal Rearrangements Generate New Gene Products