Inversions can have an effect on the phenotype of the organism when
A)the trancscirbed region of a gene spans one or more of the inversion's breakpoints.
B)the inversion's breakpoints do not alter any of the inverted segments gene sequences.
C)the inversion is pericentric.
D)the inversion is paracentric.

Question

Quizplus · Accepted Answer

Inversions can lead to altered gene expression when the transcribed region of a gene spans one or more of the inversion's breakpoints. This can occur because the inversion may change the orientation of the gene, which can affect its regulation and expression.

Answer: C and D
 The location of the inversion can affect its impact on the phenotype. Inversions that include the centromere (pericentric) can alter the orientation of genes relative to their position on the chromosome and cause abnormal chromosome segregation during meiosis, leading to altered phenotypes. Paracentric inversions, which do not include the centromere, do not usually affect chromosome segregation but can still influence phenotype if they interrupt critical genes or regulatory sequences.

Inversions Can Have an Effect on the Phenotype of the Organism