Which of the following is not a piece of evidence that supports the radial loop-scaffold model of DNA packaging?
A)Histone-depleted metaphase chromosomes still maintain their X-like shapes.
B)Electron micrographs of whole-mounted mitotic chromosomes show loops of chromatin at the periphery of the chromosomes.
C)Topoisomerase II assists in 100Å packaging.
D)Special, irregularly spaced repetitive base sequences associate with nonhistone proteins to define the chromatin loops.

Question

Quizplus · Accepted Answer

Topoisomerase II is involved in the untangling and decatenation of DNA, not specifically in the 100Å packaging, which is more related to the nucleosome structure rather than the radial loop-scaffold model.

Which of the Following Is Not a Piece of Evidence