When constructing a YAC, why must a large amount of random DNA be included?
A)The random DNA base pairs with DNA in the natural chromosomes of a cell.
B)YACs that are too small do not segregate properly during mitosis and the random DNA is used as filler.
C)The random DNA functions as telomeres.
D)The random DNA contains origins of replication needed for maintenance of the YAC.
E)The random DNA allows YACs to be used in both eukaryotic and prokaryotic cells.

Question

Quizplus · Accepted Answer

YACs (Yeast Artificial Chromosomes) need to be of a certain size to segregate properly during mitosis, and random DNA is used as filler to ensure they are large enough.

When Constructing a YAC, Why Must a Large Amount of Random