A mutation that occurs when a base is inserted into or deleted from a DNA sequence, completely altering the subsequent amino acid sequence, is called a
A)frameshift mutation.
B)missense mutation.
C)silent mutation.
D)nonsense mutation.

Question

Quizplus · Accepted Answer

A frameshift mutation occurs when one or more bases are inserted into or deleted from a DNA sequence, causing a change in the reading frame of the sequence, and altering the subsequent amino acid sequence. This can have significant effects on the resulting protein, potentially leading to a loss of function or the production of a non-functional protein. Missense mutations, in contrast, involve a single base substitution that leads to the replacement of one amino acid with another. Silent mutations result in no change to the resulting protein sequence, while nonsense mutations introduce a premature stop codon, leading to a truncated, incomplete protein.

A Mutation That Occurs When a Base Is Inserted into or Deleted