Mutations that abolish the function encoded by the wild-type allele are known as
A)null mutations.
B)hypomorphic mutations.
C)hypermorphic mutations.
D)conditional mutations.
E)neomorphic mutations. Blooms Level 2: Understand

Question

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Null mutations completely eliminate or abolish the function of the protein encoded by the wild-type allele, and are also known as loss-of-function mutations. Hypomorphic mutations, on the other hand, reduce the activity of the protein, while hypermorphic mutations increase its activity. Conditional mutations have their effect depending on certain environmental or genetic conditions, and neomorphic mutations create a novel or ectopic function that is not present in the wild-type protein.

Mutations That Abolish the Function Encoded by the Wild-Type Allele