HIS4/trp1; HIS4/TRP1; his4/TRP1; his4/trp1

Question

Quizplus · Accepted Answer

Since HIS4 and TRP1 are located on different chromosomes, the alleles are unlinked and thus undergo independent assortment during meiosis. Therefore, the genotype of one locus is not affected by the genotype of the other locus. This means that the genotypes HIS4/trp1, HIS4/TRP1, his4/TRP1, and his4/trp1 are all possible and equally likely, resulting in a test cross ratio of 1:1:1:1. Therefore, the offspring of a cross between two individuals with these genotypes would show a classic Mendelian pattern of segregation and be able to undergo independent assortment. Thus, this scenario would be considered a true classic Mendelian test cross and would result in a 1:1:1:1 ratio of genotypes.

HIS4/trp1; HIS4/TRP1; His4/TRP1; His4/trp1