If you were studying fruit flies and found that every time you began an experiment on a gene with one allele leading to blindness when found in homozygous condition,there were always more heterozygotes with this allele than expected,you might suspect that the heterozygote had some selective advantge.

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Heterozygotes for some alleles which are sriously deleterious in the homozygous condition,may have a slective advantage,as is the case for the blood disease sickel cell anemia.Heterozygotes for the defective sickle cell allele are resitant to infection with malaria.Please see section 12.5 for more information.

If You Were Studying Fruit Flies and Found That Every