If the frequency of an autosomal recessive trait in humans is 1 out of 4000 births,what would be the expected frequency of heterozygote carriers for the trait if we assume that the gene is in Hardy-Weinberg equilibrium?
A)0.00025
B)0.0158
C)0.031
D)0.969
E)0.984

Question

Quizplus · Accepted Answer

The frequency of the recessive allele (q) is the square root of 1/4000, which is 0.0158. The frequency of heterozygotes (2pq) is approximately 2 * 0.9842 * 0.0158 = 0.031.

If the Frequency of an Autosomal Recessive Trait in Humans