If the centrioles are mispositioned in the cell,a functional mitotic spindle will fail to form.In this situation,how will chromosome segregation be affected?
A)Microtubules will not attach to the kinetochores.
B)The sister chromatids will be pulled apart and equally divided among daughter cells.
C)All of the chromosomes will go to one of the daughter cells.
D)Sister chromatids will not be divided equally among daughter cells.

Question

Quizplus · Accepted Answer

If the centrioles are mispositioned and a functional mitotic spindle fails to form, sister chromatids will not be divided equally among daughter cells. This is because the spindle fibers, which are responsible for separating the sister chromatids, will not be able to attach properly to the chromosomes or to pull them apart, leading to an unequal distribution of genetic material. Therefore, incorrect positioning of centrioles can result in aneuploidy, a condition where there is an abnormal number of chromosomes in the daughter cells.

If the Centrioles Are Mispositioned in the Cell,a Functional Mitotic