Most protein-enzymes are

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Most protein-enzymes are globular proteins. This is because globular proteins have a specific three-dimensional structure that allows them to form an active site where they can bind to their substrate and catalyze a chemical reaction. Fibrous proteins, on the other hand, are long and thin and provide structural support. Hormones are signaling molecules and are not necessarily enzymes. Histones are proteins that package and organize DNA but are not enzymes. Metalloenzymes are enzymes that require a metal ion cofactor to function but are not the majority of enzymes.

Most Protein-Enzymes Are