If you were an enzyme and needed to perform the energetically unfavorable conversion of X to Y,you would

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Enzymes often couple energetically unfavorable reactions to energetically favorable reactions to drive the overall process forward. The energetically favorable reaction provides the energy needed to overcome the activation energy barrier of the energetically unfavorable reaction. This coupling is typically achieved through the formation or hydrolysis of high-energy molecules such as ATP or other activated carrier molecules. Among the options given, the only plausible choice is A, where the conversion of X to Y is coupled to a second reaction associated with a large decrease in free energy, which helps drive the energetically unfavorable reaction forward.

If You Were an Enzyme and Needed to Perform the Energetically