Which of the following mutations would be most likely to interfere with the proper insertion of a protein in the plasma membrane?

Question

Quizplus · Accepted Answer

Transmembrane domains are made up of non-polar amino acids to pass through the hydrophobic interior of the plasma membrane. A non-polar to polar amino acid substitution would disrupt the hydrophobicity and potentially interfere with proper insertion of the protein into the membrane.

Which of the Following Mutations Would Be Most Likely to Interfere