What Is NOT a Reason Why an Abscessed Wound Might

What is NOT a reason why an abscessed wound might not respond to antibiotic treatment?

A) The bacteria within the abscess have ceased replicating,and many antibiotics require actively replicating cells in order to be effective.
B) The blood vessels that would bring the drug to the area have been destroyed or clogged with clots,preventing the drug from getting to the microbes in the abscess.
C) The bacteria in an abscess have all acquired multi-drug antibiotic resistance,so any drugs that are used will have no effect.
D) The chemical composition of the pus in the abscess often inactivates antibiotic drugs,making them ineffective.