A mutation of an autosomal recessive trait can remain undetected for generations.

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Autosomal recessive traits can be masked if the individual possesses at least one dominant allele. Therefore, carriers of the recessive allele can remain unaware of their status and pass on the gene to their children, who may also remain unaffected carriers. This cycle can continue for generations until two carrier individuals have children, who have a 25% chance of inheriting two recessive alleles and expressing the trait.

A Mutation of an Autosomal Recessive Trait Can Remain Undetected