Positional cloning is used to link the inheritance of a disease in a pedigree to the inheritance of _____.
A) other diseases or conditions
B) a specific blood type
C) other genes whose loci were known
D) marker sequences produced by restriction enzymes
E) X-linked genes

Question

Quizplus · Accepted Answer

Positional cloning involves selecting a marker sequence produced by restriction enzymes that is genetically linked to the disease in question. By identifying this sequence, researchers can track the inheritance of the disease in a pedigree and ultimately identify the gene responsible for the disease. The other answer choices do not accurately describe the purpose of positional cloning.

Positional Cloning Is Used to Link the Inheritance of a Disease