When determining whether a relative is a proper match for organ or tissue donation,three sets of HLA alleles - inherited together - must match those from the intended recipient. These allele sets are known as _____.
A) open reading frames
B) splice sites
C) copy number variants
D) haplotypes
E) disease-associated mutations

Question

Quizplus · Accepted Answer

The sets of HLA alleles that must match for successful organ or tissue donation are known as haplotypes. Haplotypes refer to a set of genetic markers that are inherited together on the same chromosome, and in this case, they refer to the group of HLA alleles that are inherited together from one parent. Matching haplotypes between donor and recipient help to minimize the risk of rejection and increase the likelihood of successful transplantation.

When Determining Whether a Relative Is a Proper Match for Organ