The most common chromosomal abnormality that takes place in the autosomes is

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Down syndrome is the most common chromosomal abnormality that occurs in the autosomes, affecting approximately 1 in 700 births. It occurs due to the presence of an extra copy of chromosome 21, which leads to developmental delays, intellectual disability, and various physical features. Klinefelter's syndrome and Turner's syndrome involve sex chromosomes and affect fewer individuals compared to Down syndrome. Walker syndrome is not an existing chromosomal abnormality.

The Most Common Chromosomal Abnormality That Takes Place in the Autosomes