Peptide hormones bind to transmembrane protein receptors located on the surface of target cells. Once binding occurs, a signal is transduced through the intracellular domain of the receptor leading to cellular responses. Peptide hormones are not lipid-soluble and cannot pass through the plasma membrane. They also do not bind to receptors in the cytoplasm or nucleus, nor do they function as gene regulatory proteins.

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Peptide Hormones

Question 17

Multiple Choice

Peptide hormones

A) are lipid-soluble and easily pass through a plasma membrane.
B) bind selectively to receptor molecules in the cytoplasm.
C) bind selectively to receptor molecules in the nucleus.
D) form a hormone-receptor complex that is a gene regulatory protein that activates or inhibits a specific gene.
E) Bind to transmembrane protein receptors.

Correct Answer: