Of the following, the most important consideration in developing a drug that will act in the brain is:

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The ability of a drug to cross the blood-brain barrier is crucial in developing drugs that act in the brain. This barrier serves to protect the brain from foreign substances and only allows certain molecules to pass through. Therefore, a drug that cannot cross this barrier would not be effective in treating conditions that affect the brain.

Of the Following, the Most Important Consideration in Developing a Drug