Which of the following would produce a hyperpolarization of a neuron?

Question

Quizplus · Accepted Answer

Applying a negative charge inside the neuron with a microelectrode would increase the negative charge inside the neuron and make it more difficult for the neuron to depolarize and fire an action potential, resulting in a hyperpolarization. B is incorrect because applying a positive charge inside the neuron would depolarize the neuron and make it more likely to fire an action potential, resulting in an increase in membrane potential. C is incorrect because increasing membrane permeability to sodium would allow more positively charged sodium ions into the neuron, which would depolarize the neuron and make it more likely to fire an action potential. Similarly, D is incorrect because decreasing membrane permeability to potassium would cause a buildup of positively charged potassium ions inside the neuron, which would also depolarize the neuron and make it more likely to fire an action potential.

Which of the Following Would Produce a Hyperpolarization of a Neuron