Which of the following would be the most promising treatment for Huntington's disease?

Question

Quizplus · Accepted Answer

Blocking formation of glutamine chain clustering would be the most promising treatment for Huntington's disease as the disease is caused by the abnormal accumulation of clustered glutamine chains in the brain. By blocking this formation, the progression of the disease could be slowed or even stopped. Enhancing formation of glutamine chains (A) would be counterproductive, as this is the root cause of the disease. Increasing production of huntingtin (B) could potentially worsen the disease as the mutated huntingtin protein is the cause of the disease. Decreasing production of BDNF (D) would also not be a promising treatment as this protein has neuroprotective effects and decreasing it could actually worsen the disease.

Which of the Following Would Be the Most Promising Treatment