Huntington's disease may also affect orexin-containing neurons in the hypothalamus, leading to symptoms similar to:

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Huntington's disease can affect the orexin-containing neurons in the hypothalamus, which are responsible for regulating sleep-wake cycles. Damage to these neurons can lead to decreased production of orexin, causing symptoms similar to narcolepsy, such as excessive daytime sleepiness, sudden loss of muscle tone, and hallucinations during sleep paralysis.

Huntington's Disease May Also Affect Orexin-Containing Neurons in the Hypothalamus