To estimate the amount of serotonin turnover in the brain, investigators measure the amount of ____ in the blood or cerebrospinal fluid.

Question

Quizplus · Accepted Answer

5-HIAA is a breakdown product of serotonin that is found in the blood and cerebrospinal fluid. By measuring the amount of 5-HIAA, investigators can estimate the amount of serotonin turnover in the brain. COMT and MAO are enzymes involved in the breakdown of neurotransmitters, but they are not specific to serotonin. MPTP is a chemical that is toxic to neurons and is not used to measure serotonin turnover.

To Estimate the Amount of Serotonin Turnover in the Brain