A Patient,who Has Intermittent Claudication,has Been Taking 400 Mg of Pentoxifylline

A patient,who has intermittent claudication,has been taking 400 mg of pentoxifylline (Trental) three times daily with meals for 2 weeks.The patient calls the clinic and reports mild flushing,occasional gastrointestinal upset,and continued pain in both legs.How will the nurse advise the patient?

A) "Expect side effects to diminish as drug effects increase in several weeks."
B) "Notify the provider of the continued pain and request increasing the dose."
C) "Take a daily aspirin tablet to enhance the effects of pentoxifylline."
D) "Take the medication 1 hour before or 2 hours after a meal."