In __________, because the frozen sample remains hydrated, the biological molecules retain the same conformation as in solution.

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Cryo-EM, or cryogenic electron microscopy, uses a technique of freezing biological samples at very low temperatures to obtain high-resolution images of the structures. The frozen sample remains hydrated, which helps to retain the original conformation and structure of the biological molecules, unlike other imaging techniques such as TEM or SEM which involve drying and/or staining the sample.

In __________, Because the Frozen Sample Remains Hydrated, the Biological