When an antibody is covering the foreign microorganism then complement may be activated via this___ pathway.

Question

Quizplus · Accepted Answer

The classical pathway of complement activation is initiated by the binding of C1 complex to a specific antibody that is bound to the surface of a foreign microorganism. Therefore, when an antibody is covering the foreign microorganism, complement may be activated via the classical pathway. The lectin pathway is initiated by the binding of mannose-binding lectin (MBL) or ficolins to the surface of microorganisms. The alternative pathway is initiated by the spontaneous hydrolysis of C3 in plasma. Interleukin is not related to complement activation.

When an Antibody Is Covering the Foreign Microorganism Then Complement