Antibodies directed to alloantigen from one organism often cross-react with an alloantigen from another organism.

Question

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Antibodies directed against alloantigens can recognize similar or identical antigens in other organisms, leading to cross-reactivity. This phenomenon is particularly relevant in the field of transplantation, where the recipient's immune system can mount a response against the donor's foreign tissue, but also against similar antigens found in other individuals or species.

Antibodies Directed to Alloantigen from One Organism Often Cross-React with an Alloantigen