Which two antibiotics affect the DNA and RNA of bacteria?

Name: Which two antibiotics affect the DNA and RNA of bacteria?
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Rifampin and quinolones are antibiotics that affect the DNA and RNA of bacteria. Rifampin works by binding to bacterial RNA polymerase, which prevents the transcription of mRNA from DNA. Quinolones, such as ciprofloxacin and levofloxacin, work by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes involved in the replication and maintenance of bacterial DNA.

Which Two Antibiotics Affect the DNA and RNA of Bacteria