Successful anti-HIV drug therapies today work by blocking the action of viral reverse transcriptase.Select which step of virus multiplication that would be directly blocked by this mechanism:

Question

Quizplus · Accepted Answer

The step of virus multiplication that is directly blocked by anti-HIV drug therapies that target viral reverse transcriptase is synthesis. Reverse transcriptase is a viral enzyme that catalyzes the conversion of the viral RNA genome into DNA, which is then integrated into the host cell genome to produce more viral particles. By blocking the action of reverse transcriptase, the viral replication cycle is disrupted, and fewer viral particles are produced. Anti-HIV drug therapies that target reverse transcriptase include nucleoside analogs, non-nucleoside reverse transcriptase inhibitors (NNRTIs), and integrase inhibitors.

Successful Anti-HIV Drug Therapies Today Work by Blocking the Action