The difference in cell wall structure of Mycobacterium and Nocardia compared to the typical gram-positive bacterial cell wall structure is

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Mycobacterium and Nocardia have a unique, waxy lipid called mycolic acid in their cell walls, which is not found in typical gram-positive bacteria. This makes them resistant to certain antimicrobial agents and difficult to stain with traditional gram-staining techniques. They also have less peptidoglycan compared to typical gram-positive bacteria and do not have lipopolysaccharide as found in gram-negative bacteria.

The Difference in Cell Wall Structure of Mycobacterium and Nocardia